BDBM107753 US8598217, 99

SMILES CN1CCC(NC(=O)c2ccc3nc(C(=O)c4ccnc(-c5cncc6ccccc56)c4)[nH]c3c2)CC1

InChI Key InChIKey=CUWJNDQSCHRSLF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 107753   

TargetCyclin-dependent kinase 4(Rabbit)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 107753BDBM107753(US8598217, 99)
Affinity DataIC50: 26nMpH: 7.5Assay Description:A 384-well microtiter Lance TR-FRET (time-resolved-fluorescence energy transfer) endpoint assay was used for CDK4/cyclin D1 kinase activity measureme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2014
Entry Details
US Patent