BDBM10793 7-(prop-2-yn-1-ylamino)-5,6,7,8-tetrahydronaphthalen-2-yl N-ethyl-N-methylcarbamate::aminotetralin deriv. 28b

SMILES CCN(C)C(=O)Oc1ccc2CCC(Cc2c1)NCC#C

InChI Key InChIKey=LHCNMMLMHAYVJW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 10793   

TargetCarboxylic ester hydrolase(Horse)
Teva Pharmaceutical Industries

LigandPNGBDBM10793(7-(prop-2-yn-1-ylamino)-5,6,7,8-tetrahydronaphthal...)
Affinity DataIC50: 290nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Teva Pharmaceutical Industries

LigandPNGBDBM10793(7-(prop-2-yn-1-ylamino)-5,6,7,8-tetrahydronaphthal...)
Affinity DataIC50: 2.00E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Teva Pharmaceutical Industries

LigandPNGBDBM10793(7-(prop-2-yn-1-ylamino)-5,6,7,8-tetrahydronaphthal...)
Affinity DataIC50: 1.20E+5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Teva Pharmaceutical Industries

LigandPNGBDBM10793(7-(prop-2-yn-1-ylamino)-5,6,7,8-tetrahydronaphthal...)
Affinity DataIC50: 2.04E+5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed