BDBM108731 US8604016, 310::US9938267, Cmpd ID 310

SMILES O=C(Cc1ccccc1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccccn3)s2)s1

InChI Key InChIKey=KXELOZBBTFJOQP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 108731   

TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM108731(US8604016, 310 | US9938267, Cmpd ID 310)
Affinity DataIC50: 70nMAssay Description:Inhibition of human kidney type glutaminase (124 to 669 residues) using L-[3H]-glutamine as substrate after 45 mins by topcount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM108731(US8604016, 310 | US9938267, Cmpd ID 310)
Affinity DataIC50: 83nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2014
Entry Details
US Patent

TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM108731(US8604016, 310 | US9938267, Cmpd ID 310)
Affinity DataIC50: 83nMAssay Description:No preinc (Column 4).More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent