BDBM109115 US8609852, 117::US8609852, 34

SMILES Cc1[nH+]c(cs1)C#Cc1cnc(NC(C)(C)C)nc1

InChI Key InChIKey=AHPAEEOLNJMEOV-UHFFFAOYSA-O

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 109115   

TargetMetabotropic glutamate receptor 5(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM109115(US8609852, 117 | US8609852, 34)
Affinity DataKi:  0.900nM ΔG°:  -12.3kcal/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2014
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 5(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM109115(US8609852, 117 | US8609852, 34)
Affinity DataKi:  1nM ΔG°:  -12.3kcal/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2014
Entry Details
Go to US Patent