BDBM109137 US8609852, 44

SMILES Cc1nc(cs1)C#Cc1ccc([nH+]c1)-c1ccccc1CO

InChI Key InChIKey=IYSHBKDIOZKXRH-UHFFFAOYSA-O

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 109137   

TargetMetabotropic glutamate receptor 5(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM109137(US8609852, 44)
Affinity DataKi:  2nM ΔG°:  -11.9kcal/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2014
Entry Details
Go to US Patent