BDBM10923 3-{[methyl({3-[(2-oxo-2H-chromen-7-yl)oxy]propyl})amino]methyl}phenyl N-methylcarbamate hydrochloride::CHEMBL340625::aminoalkoxyheteroaryl deriv. 16

SMILES CNC(=O)Oc1cccc(CN(C)CCCOc2ccc3ccc(=O)oc3c2)c1

InChI Key InChIKey=XVJDMVSHDMGRQA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 10923   

TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10923(CHEMBL340625 | 3-{[methyl({3-[(2-oxo-2H-chromen-7-...)
Affinity DataIC50: 5.70nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Bologna

LigandPNGBDBM10923(CHEMBL340625 | 3-{[methyl({3-[(2-oxo-2H-chromen-7-...)
Affinity DataIC50: 3.60nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10923(CHEMBL340625 | 3-{[methyl({3-[(2-oxo-2H-chromen-7-...)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10923(CHEMBL340625 | 3-{[methyl({3-[(2-oxo-2H-chromen-7-...)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of acetylcholinesterase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article