BDBM111185 US10112950, Example 37::US10556908, Example 37::US9695180, 37
SMILES CNC(=O)c1cn2c(-c3ccc(C)cc3)c(nc(OC[C@@H]3CCNC3)c2n1)-c1ccc(cc1)C#N
InChI Key InChIKey=PEWKCACKUBGFCI-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 111185
Affinity DataIC50: 50nMpH: 7.5 T: 2°CAssay Description:10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 mM NaCl, 5 mM DTT) were preincubated ...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMpH: 7.5Assay Description:LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair