BDBM111475 US8618286, 1

SMILES CN1CCCC1CCN1C(=O)COc2cc(ccc12)N=C(N)c1cccs1

InChI Key InChIKey=MFZCZNMFRYGETK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 111475   

TargetNitric oxide synthase, brain(Human)
Neuraxon

US Patent
LigandPNGBDBM111475(US8618286, 1)
Affinity DataIC50: 2.08E+3nMAssay Description:Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2014
Entry Details
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TargetNitric oxide synthase, endothelial(Human)
Neuraxon

US Patent
LigandPNGBDBM111475(US8618286, 1)
Affinity DataIC50: 8.72E+4nMAssay Description:Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2014
Entry Details
Go to US Patent

TargetNitric oxide synthase, inducible(Human)
Neuraxon

US Patent
LigandPNGBDBM111475(US8618286, 1)
Affinity DataIC50: 1.00E+5nMAssay Description:Recombinant human inducible NOS (iNOS) was produced in Baculovirus-infected Sf9 cells (ALEXIS). In a radiometric method, NO synthase activity was det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2014
Entry Details
Go to US Patent