BDBM11152 (1S,2S)-1-(dimethylcarbamoyl)-3-oxo-3-(pyrrolidin-1-yl)-1-(4-{[1,2,4]triazolo[1,5-a]pyridin-6-yl}phenyl)propan-2-aminium; 2,2,2-trifluoroacetate::(2S,3S)-4-(dimethylamino)-1,4-dioxo-1-pyrrolidin-1-yl-3-(4-[1,2,4]triazolo[1,5-a]pyridin-6-ylphenyl)butan-2-aminium trifluoroacetate::Biarylphenylalanine Amide 31

SMILES CN(C)C(=O)[C@H]([C@H]([NH3+])C(=O)N1CCCC1)c1ccc(cc1)-c1ccc2ncnn2c1

InChI Key InChIKey=XIOZPPFALAYTMC-UHFFFAOYSA-O

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 11152   

TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM11152((1S,2S)-1-(dimethylcarbamoyl)-3-oxo-3-(pyrrolidin-...)
Affinity DataIC50: 5.20nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Merck Research Laboratories

LigandPNGBDBM11152((1S,2S)-1-(dimethylcarbamoyl)-3-oxo-3-(pyrrolidin-...)
Affinity DataIC50: 1.00E+5nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

LigandPNGBDBM11152((1S,2S)-1-(dimethylcarbamoyl)-3-oxo-3-(pyrrolidin-...)
Affinity DataIC50: 1.00E+5nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck Research Laboratories

LigandPNGBDBM11152((1S,2S)-1-(dimethylcarbamoyl)-3-oxo-3-(pyrrolidin-...)
Affinity DataIC50: 1.40E+4nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2006
Entry Details Article
PubMed