BDBM111688 US8618111, B-75
SMILES CN1CCC2(CCN(CC2)c2ncnc(C)c2C#Cc2ccc(N)nc2)C1=O
InChI Key InChIKey=RPGVCJCDFFOBDB-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 111688
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 48nMpH: 7.5 T: 2°CAssay Description:PI3Kalpha assay described herein provides IC50 values indicating the activity of the compounds inhibiting PI3 kinase alpha activity Inhibition of PI3...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...More data for this Ligand-Target Pair