BDBM1124 (4R,5S,6S)-4-benzyl-6-(1-bromo-2-phenylethyl)-5-hydroxy-1,3-bis({[3-(hydroxymethyl)phenyl]methyl})-1,3-diazinan-2-one::(4S,5S,6R)-Tetrahydro-1,3-bis-[3-(hydroxymethyl)phenylmethyl]-5-hydroxy-4-(1S-bromo-2-phenylethyl)-6-(phenylmethyl)-2(1H)-pyrimidinone::Tetrahydropyrimidinone deriv. 79

SMILES OCc1cccc(CN2[C@H](Cc3ccccc3)[C@H](O)[C@@H]([C@@H](Br)Cc3ccccc3)N(Cc3cccc(CO)c3)C2=O)c1

InChI Key InChIKey=YZNMWSWYDOVEJX-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 1124   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Missouri-St. Louis

Curated by ChEMBL
LigandPNGBDBM1124((4R,5S,6S)-4-benzyl-6-(1-bromo-2-phenylethyl)-5-hy...)
Affinity DataKi:  11nMAssay Description:Inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandPNGBDBM1124((4R,5S,6S)-4-benzyl-6-(1-bromo-2-phenylethyl)-5-hy...)
Affinity DataKi:  11nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Missouri-St. Louis

Curated by ChEMBL
LigandPNGBDBM1124((4R,5S,6S)-4-benzyl-6-(1-bromo-2-phenylethyl)-5-hy...)
Affinity DataKi:  11nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2004
Entry Details Article
PubMed