BDBM11260 dipeptidomimetic unsaturated ester 18b::ethyl (2E,4S)-4-({N-[(2E)-3-(4-nitrophenyl)prop-2-enoyl]-L-phenylalanyl}amino)-5-phenylpent-2-enoate::ethyl (2E,4S)-4-[(2S)-2-[(2E)-3-(4-nitrophenyl)prop-2-enamido]-3-phenylpropanamido]-5-phenylpent-2-enoate

SMILES CCOC(=O)\C=C\[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)\C=C\c1ccc(cc1)N(=O)=O

InChI Key InChIKey=XAYRYKDJTCRRDA-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11260   

TargetReplicase polyprotein 1ab(SARS-CoV)
National Taiwan University

LigandPNGBDBM11260(ethyl (2E,4S)-4-[(2S)-2-[(2E)-3-(4-nitrophenyl)pro...)
Affinity DataKi:  2.48E+3nM ΔG°:  -7.64kcal/mole IC50: 5.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMed