BDBM112693 US8629158, 24::US8629158, 25::US8629158, 6

SMILES Cn1c2CC3CCC(N3)c2c2ccc(cc12)-n1ccc(OCc2ccc(F)cn2)cc1=O

InChI Key

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 112693   

TargetMelanin-concentrating hormone receptor 1(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM112693(US8629158, 25 | US8629158, 24 | US8629158, 6)
Affinity DataKi:  7.40nM ΔG°:  -11.1kcal/molepH: 7.4 T: 2°CAssay Description:Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
Go to US Patent

TargetMelanin-concentrating hormone receptor 1(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM112693(US8629158, 25 | US8629158, 24 | US8629158, 6)
Affinity DataKi:  13.5nM ΔG°:  -10.7kcal/molepH: 7.4 T: 2°CAssay Description:Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
Go to US Patent

TargetMelanin-concentrating hormone receptor 1(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM112693(US8629158, 25 | US8629158, 24 | US8629158, 6)
Affinity DataKi:  19nM ΔG°:  -10.5kcal/molepH: 7.4 T: 2°CAssay Description:Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
Go to US Patent