BDBM11299 Compound 1 analog 10::ethyl (2E)-2-cyano-3-({4-[(4-{[(1E)-2-cyano-3-ethoxy-3-oxoprop-1-en-1-yl]amino}benzene)sulfonyl]phenyl}amino)prop-2-enoate

SMILES CCOC(=O)C(C=Nc1ccc(cc1)S(=O)(=O)c1ccc(cc1)N=CC(C#N)C(=O)OCC)C#N

InChI Key InChIKey=SAZFDZVQWXQDCI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11299   

TargetReplicase polyprotein 1ab(SARS-CoV)
National Defense Medical Center

LigandPNGBDBM11299(ethyl (2E)-2-cyano-3-({4-[(4-{[(1E)-2-cyano-3-etho...)
Affinity DataIC50: 1.60E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMed