BDBM11714 (2S)-1-(2-{[(2S)-4-oxo-4-(1,2,3,4-tetrahydroisoquinolin-2-yl)butan-2-yl]amino}acetyl)pyrrolidine-2-carbonitrile::(2S)-Cyanopyrrolidine analogue 20a::2-[3-[2-[2-Cyano-(S)-pyrrolidin-1-yl]-2-oxoethylamino]-1-oxo-butyl]-1,2,3,4-tetrahydroisoquinoline

SMILES C[C@@H](CC(=O)N1CCc2ccccc2C1)NCC(=O)N1CCC[C@H]1C#N

InChI Key InChIKey=NZIWMJXVLALVCM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 11714   

TargetDipeptidyl peptidase 4(Human)
National Health Research Institutes

LigandPNGBDBM11714(2-[3-[2-[2-Cyano-(S)-pyrrolidin-1-yl]-2-oxoethylam...)
Affinity DataIC50: 54nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
National Health Research Institutes

LigandPNGBDBM11714(2-[3-[2-[2-Cyano-(S)-pyrrolidin-1-yl]-2-oxoethylam...)
Affinity DataIC50: 5.35E+3nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
National Health Research Institutes

LigandPNGBDBM11714(2-[3-[2-[2-Cyano-(S)-pyrrolidin-1-yl]-2-oxoethylam...)
Affinity DataIC50: 1.89E+4nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2006
Entry Details Article
PubMed