BDBM11716 (2S)-1-(2-{[2-methyl-4-oxo-4-(1,2,3,4-tetrahydroisoquinolin-2-yl)butan-2-yl]amino}acetyl)pyrrolidine-2-carbonitrile::(2S)-Cyanopyrrolidine analogue 21a::2-[3-[2-[2-Cyano-(S)-pyrrolidin-1-yl]-2-oxoethylamino]-3-methyl-1-oxobutyl]-1,2,3,4-tetrahydroisoquinoline

SMILES CC(C)(CC(=O)N1CCc2ccccc2C1)NCC(=O)N1CCC[C@H]1C#N

InChI Key InChIKey=VKFKZRVCMJZWMP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 11716   

TargetDipeptidyl peptidase 4(Human)
National Health Research Institutes

LigandPNGBDBM11716((2S)-1-(2-{[2-methyl-4-oxo-4-(1,2,3,4-tetrahydrois...)
Affinity DataIC50: 49nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
National Health Research Institutes

LigandPNGBDBM11716((2S)-1-(2-{[2-methyl-4-oxo-4-(1,2,3,4-tetrahydrois...)
Affinity DataIC50: 3.42E+4nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
National Health Research Institutes

LigandPNGBDBM11716((2S)-1-(2-{[2-methyl-4-oxo-4-(1,2,3,4-tetrahydrois...)
Affinity DataIC50: 1.00E+5nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2006
Entry Details Article
PubMed