BDBM118948 US9682940, 257

SMILES OC(=O)c1cccc(CN2CCC(CC2)c2n(nc3ccc(cc23)C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)C2CC2)c1

InChI Key InChIKey=KMMCEVXUSXMDBE-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 118948   

TargetCannabinoid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM118948(US9682940, 257)
Affinity DataEC50:  13nMAssay Description:CB1 and CB2 receptors are Gi-coupled GPCR. Activation of CB1 and CB2 receptors results in a decrease in cAMP production. An inverse agonist of the CB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM118948(US9682940, 257)
Affinity DataEC50: >5.00E+3nMAssay Description:CB1 and CB2 receptors are Gi-coupled GPCR. Activation of CB1 and CB2 receptors results in a decrease in cAMP production. An inverse agonist of the CB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
US Patent