BDBM11898 (2S)-2-amino-N-[(1R)-1-cyanoethyl]-N,3,3-trimethylbutanamide::seco-proline-based inhibitor 14

SMILES [H][C@@](N)(C(=O)N(C)[C@H](C)C#N)C(C)(C)C

InChI Key InChIKey=KNARVBXGIRZZRK-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11898   

TargetDipeptidyl peptidase 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM11898((2S)-2-amino-N-[(1R)-1-cyanoethyl]-N,3,3-trimethyl...)
Affinity DataKi: >1.00E+4nM ΔG°: >-6.75kcal/molepH: 7.4 T: 2°CAssay Description:Inhibition of human DPP-IV activity was measured under steady-state conditions by following the absorbance increase at 405 nm upon the substrate clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed