BDBM11923 substituted diprolyl nitrile 16::tert-butyl N-[(3S,5S)-5-{[(1S,3S,5S)-3-cyano-2-azabicyclo[3.1.0]hexan-2-yl]carbonyl}pyrrolidin-3-yl]carbamate

SMILES CC(C)(C)OC(=O)N[C@@H]1CN[C@@H](C1)C(=O)N1[C@H]2C[C@H]2C[C@H]1C#N

InChI Key InChIKey=QOIMMXHELQXMLS-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11923   

TargetDipeptidyl peptidase 4(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM11923(tert-butyl N-[(3S,5S)-5-{[(1S,3S,5S)-3-cyano-2-aza...)
Affinity DataKi:  140nM ΔG°:  -9.25kcal/molepH: 7.4 T: 2°CAssay Description:Inhibition of human DPP-IV activity was measured under steady-state conditions by following the absorbance increase at 405 nm upon the substrate clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2006
Entry Details Article
PubMed