BDBM11975 (3R)-3-amino-1-{2-cyclopropyl-4H,5H,6H,7H-pyrido[3,4-d][1,3]oxazol-5-yl}-4-(2,5-difluorophenyl)butan-1-one::oxazolopiperidine 77

SMILES N[C@@H](CC(=O)N1CCc2oc(nc2C1)C1CC1)Cc1cc(F)ccc1F

InChI Key InChIKey=UDXLNEJSRGJBIP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 11975   

TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM11975((3R)-3-amino-1-{2-cyclopropyl-4H,5H,6H,7H-pyrido[3...)
Affinity DataIC50: 180nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Merck Research Laboratories

LigandPNGBDBM11975((3R)-3-amino-1-{2-cyclopropyl-4H,5H,6H,7H-pyrido[3...)
Affinity DataIC50: 1.00E+5nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

LigandPNGBDBM11975((3R)-3-amino-1-{2-cyclopropyl-4H,5H,6H,7H-pyrido[3...)
Affinity DataIC50: 5.10E+4nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck Research Laboratories

LigandPNGBDBM11975((3R)-3-amino-1-{2-cyclopropyl-4H,5H,6H,7H-pyrido[3...)
Affinity DataIC50: 1.00E+5nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMed