BDBM12037 3-(4-chlorophenyl)-1-{4-[(2E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]phenyl}urea::Phenylurenyl Chalcone deriv. 27

SMILES COc1cc(\C=C\C(=O)c2ccc(NC(=O)Nc3ccc(Cl)cc3)cc2)cc(OC)c1OC

InChI Key InChIKey=FJSIXXPLIBJTLS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12037   

TargetFalcipain-2(malaria parasite P. falciparum)
Universidad Central De Venezuela

LigandPNGBDBM12037(3-(4-chlorophenyl)-1-{4-[(2E)-3-(3,4,5-trimethoxyp...)
Affinity DataIC50: 1.80E+3nMpH: 5.5 T: 2°CAssay Description:The substrate peptide terminating in AMC is processed by falcipain-2 with or without inhibitors, and the accumulation of AMC was monitored in a Labsy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2006
Entry Details Article
PubMed