BDBM120815 (Z)-4-(((3-fluoro-4-((6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy) quinolin-4-yl)oxy)phenyl)amino)methylene)-3-methyl-1- (2-(trifluoromethyl)phenyl)-1H-pyrazol-5(4H)-one (13)

SMILES COc1cc2c(Oc3ccc(cc3F)N=Cc3c(C)[nH]n(-c4ccccc4C(F)(F)F)c3=O)ccnc2cc1OCCCN1CCCC1

InChI Key InChIKey=AOYGMCYJEQOPMG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 120815   

TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

LigandPNGBDBM120815((Z)-4-(((3-fluoro-4-((6-methoxy-7-(3-(pyrrolidin-1...)
Affinity DataIC50: 5.04nMpH: 7.0 T: 2°CAssay Description:The c-Met kinase activity was evaluated by homogeneous time-resolved fluorescence (HTRF) assays. In a 384-well plate, 20 µg/mL (Glue, Tyr) 4:1 w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2014
Entry Details Article
PubMed