BDBM120845 US8716478, D231::US9499570, D231

SMILES CC(=O)CCCOc1nc(Oc2ccc3B(O)OCc3c2)c(Cl)cc1C#N

InChI Key InChIKey=BEYCUVURKUGSEQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 120845   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM120845(US8716478, D231 | US9499570, D231)
Affinity DataIC50: 0.800nMpH: 7.5 T: 2°CAssay Description:Inhibition of the human PDE4 enzyme, using semi-purified enzyme from human U937 cells. The PDE4 enzyme was partially purified from human U937 myeloid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2014
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM120845(US8716478, D231 | US9499570, D231)
Affinity DataIC50: 0.800nMpH: 7.5Assay Description:Inhibition of the human PDE4 enzyme, using semi-purified enzyme from human U937 cells. The PDE4 enzyme was partially purified from human U937 myeloid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
Go to US Patent