BDBM12099 3-Amino-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole 17::N-butyl-3-{2-[4-(2-oxopyrrolidin-1-yl)phenyl]acetamido}-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-5-carboxamide

SMILES CCCCNC(=O)N1Cc2n[nH]c(NC(=O)Cc3ccc(cc3)N3CCCC3=O)c2C1

InChI Key InChIKey=ACXFBDRQBQFLGH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12099   

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

LigandPNGBDBM12099(N-butyl-3-{2-[4-(2-oxopyrrolidin-1-yl)phenyl]aceta...)
Affinity DataIC50: 51nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2006
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Nerviano Medical Sciences

LigandPNGBDBM12099(N-butyl-3-{2-[4-(2-oxopyrrolidin-1-yl)phenyl]aceta...)
Affinity DataIC50: 1.00E+4nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2006
Entry Details Article
PubMed