BDBM12184 (2S)-2-amino-2-cyclohexyl-1-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethan-1-one::CHEMBL361235::isoquinoline derivative 7

SMILES N[C@@H](C1CCCCC1)C(=O)N1CCc2ccccc2C1

InChI Key InChIKey=JZWIQUOOJPLTGM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 12184   

TargetDipeptidyl peptidase 8(Human)
National Health Research Institutes

LigandPNGBDBM12184(CHEMBL361235 | (2S)-2-amino-2-cyclohexyl-1-(1,2,3,...)
Affinity DataIC50: 3.02E+3nMpH: 8.0 T: 2°CAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
National Health Research Institutes

LigandPNGBDBM12184(CHEMBL361235 | (2S)-2-amino-2-cyclohexyl-1-(1,2,3,...)
Affinity DataIC50: 1.00E+5nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
National Health Research Institutes

LigandPNGBDBM12184(CHEMBL361235 | (2S)-2-amino-2-cyclohexyl-1-(1,2,3,...)
Affinity DataIC50: 1.00E+5nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
National Health Research Institutes

LigandPNGBDBM12184(CHEMBL361235 | (2S)-2-amino-2-cyclohexyl-1-(1,2,3,...)
Affinity DataIC50: 2.30E+5nMAssay Description:Inhibition of human DPP4 expressed in baculovirus systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed