BDBM12240 AZD0530 analogue 18::N-(5-Chloro-1,3-benzodioxol-4-yl)-7-[(1-methylpiperidin-4-yl-)methoxy]-5-(tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine::N-(5-chloro-2H-1,3-benzodioxol-4-yl)-7-[(1-methylpiperidin-4-yl)methoxy]-5-(oxan-4-yloxy)quinazolin-4-amine

SMILES CN1CCC(COc2cc(OC3CCOCC3)c3c(Nc4c5OCOc5ccc4Cl)ncnc3c2)CC1

InChI Key InChIKey=YQPAFFIGFWEPLF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12240   

LigandPNGBDBM12240(N-(5-chloro-2H-1,3-benzodioxol-4-yl)-7-[(1-methylp...)
Affinity DataIC50: 6nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2006
Entry Details Article
PubMed
LigandPNGBDBM12240(N-(5-chloro-2H-1,3-benzodioxol-4-yl)-7-[(1-methylp...)
Affinity DataIC50: 2.00E+3nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2006
Entry Details Article
PubMed