BDBM12250 AZD0530 analogue 28::N-(5-Chloro-1,3-benzodioxol-4-yl)-7-(2-fluoroethoxy)-5-[(1-methylpiperidin-4-yl)oxy]quinazolin-4-amine::N-(5-chloro-2H-1,3-benzodioxol-4-yl)-7-(2-fluoroethoxy)-5-[(1-methylpiperidin-4-yl)oxy]quinazolin-4-amine

SMILES CN1CCC(CC1)Oc1cc(OCCF)cc2ncnc(Nc3c4OCOc4ccc3Cl)c12

InChI Key InChIKey=KCOQHIMIYASHED-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12250   

LigandPNGBDBM12250(N-(5-Chloro-1,3-benzodioxol-4-yl)-7-(2-fluoroethox...)
Affinity DataIC50: 4nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2006
Entry Details Article
PubMed
LigandPNGBDBM12250(N-(5-Chloro-1,3-benzodioxol-4-yl)-7-(2-fluoroethox...)
Affinity DataIC50: 2.00E+4nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2006
Entry Details Article
PubMed