BDBM12251 AZD0530 analogue 29::N-(5-chloro-2H-1,3-benzodioxol-4-yl)-5-[(1-methylpiperidin-4-yl)oxy]-7-(2-methylpropoxy)quinazolin-4-amine

SMILES CC(C)COc1cc(OC2CCN(C)CC2)c2c(Nc3c4OCOc4ccc3Cl)ncnc2c1

InChI Key InChIKey=CFEJJQZWMZTARJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12251   

LigandPNGBDBM12251(N-(5-chloro-2H-1,3-benzodioxol-4-yl)-5-[(1-methylp...)
Affinity DataIC50: 7nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2006
Entry Details Article
PubMed
LigandPNGBDBM12251(N-(5-chloro-2H-1,3-benzodioxol-4-yl)-5-[(1-methylp...)
Affinity DataIC50: 1.00E+4nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2006
Entry Details Article
PubMed