BDBM123790 1-[(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4- yl)methyl]thiourea (5c)

SMILES Cc1[nH]n(-c2ccccc2)c(=O)c1CNC(N)=S

InChI Key InChIKey=WHFLNDJJRUEOBD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 123790   

TargetProstaglandin G/H synthase 2(Sheep)
Y.B. Chavan College of Pharmacy

LigandPNGBDBM123790(1-[(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol...)
Affinity DataIC50: 8.50E+4nMT: 2°CAssay Description:The COX-1/COX-2 inhibition assay was done using an enzyme immunoassay (EIA) kit. The reaction buffer (960 uL), containing 0.1 M Tris-HCl (pH 8.0), 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Y.B. Chavan College of Pharmacy

LigandPNGBDBM123790(1-[(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol...)
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:The COX-1/COX-2 inhibition assay was done using an enzyme immunoassay (EIA) kit. The reaction buffer (960 uL), containing 0.1 M Tris-HCl (pH 8.0), 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMed