BDBM124888 US8759341, 8

SMILES Cc1[nH]nc2ccc(cc12)C1C([N+]#[C-])C(C)=NC2=C1C(=O)NC2

InChI Key InChIKey=PYYVVGWOCLORHM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 124888   

TargetHepatocyte growth factor receptor(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM124888(US8759341, 8)
Affinity DataIC50: 110nMpH: 7.0 T: 2°CAssay Description:Recombinant human c-Met protein (Invitrogen, Carlsbad, Calif., USA) is used. As substrate for the kinase reaction the peptide KKKSPGEYVNIEFG (JPT, Ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2014
Entry Details
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TargetHepatocyte growth factor receptor(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM124888(US8759341, 8)
Affinity DataIC50: 250nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 mL of a 100-fold concentrated solution of the test compound in DMSO is pipetted into a black low-volume 384-well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2014
Entry Details
Go to US Patent