BDBM124895 US8759341, 38

SMILES Cc1n[nH]c2cc(F)c(cc12)C1C2C(=O)OCC2=NC(=C1[N+]#[C-])C(F)(F)F

InChI Key InChIKey=AALHLPVAYBUAFB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 124895   

TargetHepatocyte growth factor receptor(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM124895(US8759341, 38)
Affinity DataIC50: 20nMpH: 7.0 T: 2°CAssay Description:Recombinant human c-Met protein (Invitrogen, Carlsbad, Calif., USA) is used. As substrate for the kinase reaction the peptide KKKSPGEYVNIEFG (JPT, Ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2014
Entry Details
Go to US Patent

TargetHepatocyte growth factor receptor(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM124895(US8759341, 38)
Affinity DataIC50: 20nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 mL of a 100-fold concentrated solution of the test compound in DMSO is pipetted into a black low-volume 384-well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2014
Entry Details
Go to US Patent