BDBM125004 US8772510, 23

SMILES Cc1oc(nc1CC(C)(C)NC(=O)c1c(cnn1C)C(=O)N1CCC1)-c1ccccc1

InChI Key InChIKey=JQDKZIXPRQDAOX-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 125004   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Hoffmann-La Roche

US Patent

LigandBDBM125004(US8772510, 23)Copy SMILESCopy InChI

Affinity DataIC50: 77.9nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/24/2014
Entry Details
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