BDBM12564 6-chloro-N-[(3S)-1-[(2S)-1-(4-methylpiperazin-1-yl)-1-oxopropan-2-yl]-2-oxopyrrolidin-3-yl]naphthalene-2-sulfonamide::pyrrolidin-2-one-based inhibitor 23

SMILES C[C@H](N1CC[C@H](NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O)C(=O)N1CCN(C)CC1

InChI Key InChIKey=JMIVLNOCPDITSR-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12564   

TargetCoagulation factor X(Human)
Glaxosmithkline

LigandPNGBDBM12564(6-chloro-N-[(3S)-1-[(2S)-1-(4-methylpiperazin-1-yl...)
Affinity DataKi:  2.06E+3nM ΔG°:  -7.75kcal/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrate. The hydrolysis rates of chromogenic substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2006
Entry Details Article
PubMed