BDBM126720 US8778932, 31

SMILES CC1=NN=C(c2cc3c(cccc3s2)C(F)(F)F)c2cc3oc(=O)[nH]c3cc2C1

InChI Key InChIKey=CQMLETFIENAKAA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 126720   

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Les Laboratoires Servier

US Patent
LigandPNGBDBM126720(US8778932, 31)
Affinity DataIC50: 500nMAssay Description:The compounds are tested on HEK-293 (Human Embryonic Kidney) cells stably expressing the subunit α5 of the human GABAA receptor, and also the su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2014
Entry Details
Go to US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-1(Human)
Jain University

Curated by ChEMBL
LigandPNGBDBM126720(US8778932, 31)
Affinity DataIC50: 479nMAssay Description:Antagonist activity at human GABA-A alpha1 receptor expressed in HEK293 cell membranes assessed as inhibition of GABA-induced response preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Les Laboratoires Servier

US Patent
LigandPNGBDBM126720(US8778932, 31)
Affinity DataIC50: 201nMAssay Description:Antagonist activity at human GABA-A alpha5 receptor expressed in HEK293 cell membranes assessed as inhibition of GABA-induced response preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2020
Entry Details Article
PubMed