BDBM12844 1-(3-amino-1,2-benzoxazol-5-yl)-N-[4-(2-{[(3R)-3-aminopyrrolidin-1-yl]methyl}phenyl)-2-fluorophenyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide::Aminobenzisoxazole 2m

SMILES N[C@@H]1CCN(Cc2ccccc2-c2ccc(NC(=O)c3cc(nn3-c3ccc4onc(N)c4c3)C(F)(F)F)c(F)c2)C1

InChI Key InChIKey=YHIZCAWNRNQWMF-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12844   

TargetCoagulation factor X(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM12844(1-(3-amino-1,2-benzoxazol-5-yl)-N-[4-(2-{[(3R)-3-a...)
Affinity DataKi:  0.520nM ΔG°:  -12.5kcal/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2007
Entry Details Article
PubMed