BDBM1285 3-Aminopyridin-2(1H)-one analogue 5::5-ethyl-6-methyl-3-[(4,5,6,7-tetrahydro-1,3-benzoxazol-2-ylmethyl)amino]-1,2-dihydropyridin-2-one

SMILES CCc1cc(NCc2nc3CCCCc3o2)c(=O)[nH]c1C

InChI Key InChIKey=SAGDAHZQCJHXHR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 1285   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM1285(5-ethyl-6-methyl-3-[(4,5,6,7-tetrahydro-1,3-benzox...)
Affinity DataIC50: 280nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2004
Entry Details Article
PubMed