BDBM1292 3-Aminopyridin-2(1H)-one analogue 12::5-ethyl-6-methyl-3-({pyrido[2,3-d][1,3]oxazol-2-ylmethyl}amino)-1,2-dihydropyridin-2-one

SMILES CCc1cc(NCc2nc3ncccc3o2)c(=O)[nH]c1C

InChI Key InChIKey=FUUHEGQXWZMINO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 1292   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM1292(5-ethyl-6-methyl-3-({pyrido[2,3-d][1,3]oxazol-2-yl...)
Affinity DataIC50: 1.90E+3nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2004
Entry Details Article
PubMed