BDBM130643 US8822447, 141::US8822447, 153::US9771375, Example 153

SMILES CSc1nn(-c2ccccc2)c2cc(C=CC3CCNCC3)ccc12

InChI Key InChIKey=MWZJJNAYCPMYIS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 130643   

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130643(US8822447, 153 | US8822447, 141 | US9771375, Examp...)
Affinity DataIC50: 230nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130643(US8822447, 153 | US8822447, 141 | US9771375, Examp...)
Affinity DataIC50: 230nMT: 2°CAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130643(US8822447, 153 | US8822447, 141 | US9771375, Examp...)
Affinity DataIC50: 400nMT: 2°CAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130643(US8822447, 153 | US8822447, 141 | US9771375, Examp...)
Affinity DataIC50: 400nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent