BDBM131021 US8828983, 110

SMILES COC(=O)Nc1ccc2-c3nc([nH]c3Cl)[C@H](Cc3ccc(cc3)C(=O)NCc2c1)NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1

InChI Key InChIKey=IEMMEVWRBDZIOP-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 131021   

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM131021(US8828983, 110)
Affinity DataKi:  8.10E+3nMAssay Description:Inhibition of human F11a using peptide substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2020
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM131021(US8828983, 110)
Affinity DataKi:  8.12E+3nMpH: 7.4Assay Description:The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2015
Entry Details
Go to US Patent