BDBM131882 US8835444, 5.27

SMILES CCc1cc(C)n(C[C@H]2CC[C@@H](CC2)NC(=O)c2cc(ccc2Cl)C(F)(F)F)n1

InChI Key InChIKey=KUKANTJOKSAEMK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 131882   

TargetCorticotropin-releasing factor receptor 1(Human)
Novartis

US Patent
LigandPNGBDBM131882(US8835444, 5.27)
Affinity DataIC50: 13nMAssay Description:Chinese hamster ovary (CHO) cells expressing either the human or rat recombinant CRF-1 or human CRF-2alpha (Chen et al, Proc Natl Acad Sci USA 90, 89...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
Go to US Patent

TargetCorticotropin-releasing factor receptor 2(Human)
Novartis

US Patent
LigandPNGBDBM131882(US8835444, 5.27)
Affinity DataIC50: 2.03E+3nMAssay Description:Chinese hamster ovary (CHO) cells expressing either the human or rat recombinant CRF-1 or human CRF-2alpha (Chen et al, Proc Natl Acad Sci USA 90, 89...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
Go to US Patent