BDBM132057 US8841455, 152

SMILES CCc1nn(Cc2csc(n2)C(C)C)c2cccc(NC(=O)c3cnc4cc(OCCN5CCN(C)CC5)ccn34)c12

InChI Key InChIKey=FYLCAOZAZWECHN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 132057   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Array Biopharma

US Patent
LigandPNGBDBM132057(US8841455, 152)
Affinity DataIC50: 79.5nMpH: 7.3 T: 2°CAssay Description:The ability of compounds of Formula I to inhibit cFMS was determined by the following assay. cFMS enzymatic activity was measured using the LANCE Ult...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent