BDBM13250 2-N-benzene-5-N-(2-chloro-6-methylphenyl)-1,3-thiazole-2,5-diamido::BMS-354825 2-Carboxamido-4-hydrido-thiazole Analog 7r::CHEMBL131393::N-(2-Chloro-6-methylphenyl)-2-[(phenylcarbonyl)amino]-1,3-thiazole-5-carboxamide

SMILES Cc1cccc(Cl)c1NC(=O)c1cnc(NC(=O)c2ccccc2)s1

InChI Key InChIKey=GGCYNGKPFFUEPC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 13250   

TargetTyrosine-protein kinase Lck(Human)
St. John'S University

Curated by ChEMBL
LigandPNGBDBM13250(CHEMBL131393 | 2-N-benzene-5-N-(2-chloro-6-methylp...)
Affinity DataIC50: 890nMAssay Description:Inhibition of human LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2018
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
St. John'S University

Curated by ChEMBL
LigandPNGBDBM13250(CHEMBL131393 | 2-N-benzene-5-N-(2-chloro-6-methylp...)
Affinity DataIC50: 890nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2007
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
St. John'S University

Curated by ChEMBL
LigandPNGBDBM13250(CHEMBL131393 | 2-N-benzene-5-N-(2-chloro-6-methylp...)
Affinity DataIC50: 890nMAssay Description:Inhibition of CD3/CD28 T-cell proliferation assay in PBL (peripheral blood lymphocytes)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed