BDBM13283 4-amino-3-({(3S)-3-[[(7-methoxy-2-naphthyl)sulfonyl](methyl)amino]-2-oxopyrrolidin-1-yl}methyl)benzenecarboximidamide::4-amino-3-{[(3S)-3-[(7-methoxynaphthalene-2-)(methyl)sulfonamido]-2-oxopyrrolidin-1-yl]methyl}benzene-1-carboximidamide::Sulfonamidopyrrolidinone 4b

SMILES COc1ccc2ccc(cc2c1)S(=O)(=O)N(C)[C@H]1CCN(Cc2cc(ccc2N)C(N)=N)C1=O

InChI Key InChIKey=YKNCZPHUMLXMOB-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13283   

TargetCoagulation factor X(Human)
Rhone-Poulenc Rorer

LigandPNGBDBM13283(4-amino-3-{[(3S)-3-[(7-methoxynaphthalene-2-)(meth...)
Affinity DataKi:  4nM ΔG°:  -11.3kcal/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2007
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Rhone-Poulenc Rorer

LigandPNGBDBM13283(4-amino-3-{[(3S)-3-[(7-methoxynaphthalene-2-)(meth...)
Affinity DataKi:  189nM ΔG°:  -9.07kcal/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2007
Entry Details Article
PubMed