BDBM1351 3-Aminopyridin-2(1H)-one analogue 71::5-ethyl-6-methyl-3-[(naphthalen-2-ylmethyl)amino]-1,2-dihydropyridine-2-thione

SMILES CCc1cc(NCc2ccc3ccccc3c2)c(=S)[nH]c1C

InChI Key InChIKey=XUUFVGCRXHMBIL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 1351   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM1351(5-ethyl-6-methyl-3-[(naphthalen-2-ylmethyl)amino]-...)
Affinity DataIC50: 300nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2004
Entry Details Article
PubMed