BDBM13513 Sitagliptin

SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)c(F)cc1F

InChI Key InChIKey=MFFMDFFZMYYVKS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13513   

TargetDipeptidyl peptidase 4(Human)
COMSATS University Islamabad

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13513BDBM13513(Sitagliptin)
Affinity DataIC50: 8nMAssay Description:Inhibition of human DPP4 using Gly-Pro-NA as substrate incubated for 30 mins by absorbance based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Human)
COMSATS University Islamabad

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13513BDBM13513(Sitagliptin)
Affinity DataIC50: 9nMAssay Description:Inhibition of DPP4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed