BDBM135198 US8846657, 3.91

SMILES CC(C)C1C[C@@H](O)CN1c1nc2cc(nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1)-c1noc(=O)[nH]1

InChI Key InChIKey=DRCNKQOCYYDHQY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 135198   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM135198(US8846657, 3.91)
Affinity DataIC50: 1nMAssay Description:Methods: An HDM2 FRET assay was developed to assess the compounds' inhibitory activity towards binding of p53 protein. A truncated version of HDM2 wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
Go to US Patent