BDBM135439 US8846657, 18.7

SMILES COCCOc1ncc(Cl)cc1-c1nc(cc2nc(N3CCO[C@@H]4CCC[C@@H]34)n(C[C@H]3CC[C@H](C)CC3)c12)-c1noc(=O)[nH]1

InChI Key InChIKey=XGEMHWFPYIHYMV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 135439   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM135439(US8846657, 18.7)
Affinity DataIC50: 1nMAssay Description:Methods: An HDM2 FRET assay was developed to assess the compounds' inhibitory activity towards binding of p53 protein. A truncated version of HDM2 wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM135439(US8846657, 18.7)
Affinity DataIC50: 1nMAssay Description:Methods: An HDM2 FRET assay was developed to assess the compounds' inhibitory activity towards binding of p53 protein. A truncated version of HDM2 wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent