BDBM13567 2-[(4-carbamimidoylphenyl)amino]-2-{3-ethynyl-5-[(3S)-oxolan-3-yloxy]phenyl}acetic acid::phenylglycine deriv. 15

SMILES NC(=N)c1ccc(NC(C(O)=O)c2cc(O[C@H]3CCOC3)cc(c2)C#C)cc1

InChI Key InChIKey=VMITUNZSHSJLHI-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 13567   

TargetCoagulation factor VII(Human)
F. Hoffmann-La Roche

LigandPNGBDBM13567(2-[(4-carbamimidoylphenyl)amino]-2-{3-ethynyl-5-[(...)
Affinity DataKi:  65nM ΔG°:  -9.70kcal/molepH: 7.8 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
F. Hoffmann-La Roche

LigandPNGBDBM13567(2-[(4-carbamimidoylphenyl)amino]-2-{3-ethynyl-5-[(...)
Affinity DataKi:  2.60E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2007
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
F. Hoffmann-La Roche

LigandPNGBDBM13567(2-[(4-carbamimidoylphenyl)amino]-2-{3-ethynyl-5-[(...)
Affinity DataKi:  5.40E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2007
Entry Details Article
PubMed
TargetProthrombin(Human)
F. Hoffmann-La Roche

LigandPNGBDBM13567(2-[(4-carbamimidoylphenyl)amino]-2-{3-ethynyl-5-[(...)
Affinity DataKi:  9.50E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2007
Entry Details Article
PubMed