BDBM136548 US8865701, 21::US9505739, 21

SMILES O=C([C@@H]1CNC[C@]11CCc2ccccc12)N1CC[C@H](C[C@H]1c1ccccc1)c1ccccc1

InChI Key InChIKey=HMBQFZYFRSSQON-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 136548   

TargetBeta-secretase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM136548(US8865701, 21 | US9505739, 21)
Affinity DataIC50: 71nMpH: 6.5Assay Description:A homogeneous end point electrochemiluminescence (ECL) assay is performed using a biotinylated BACE substrate. The Km of the substrate is approximate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM136548(US8865701, 21 | US9505739, 21)
Affinity DataIC50: 71nMpH: 6.5Assay Description:A homogeneous end point electrochemiluminescence (ECL) assay is performed using a biotinylated BACE substrate. The Km of the substrate is approximate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
Go to US Patent