BDBM137311 US8871790, 397

SMILES CCc1cc(CC)c(cc1C(=O)N1CCC(CC1)c1ccc(cc1)C#N)-c1nc2CCN(Cc2[nH]1)C(C)=O

InChI Key InChIKey=FTOQJTNUZQCHHW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 137311   

TargetFatty acid synthase(Human)
3-V Biosciences

US Patent
LigandPNGBDBM137311(US8871790, 397 | US20250017938, Compound 001-397)
Affinity DataIC50: 40nMAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent

TargetFatty acid synthase(Human)
3-V Biosciences

US Patent
LigandPNGBDBM137311(US8871790, 397 | US20250017938, Compound 001-397)
Affinity DataIC50: 40nMAssay Description:Determination of FASN biochemical activity: The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent